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AR
Prostate Cancer Basics
By HCat at 2007-01-07 02:11

The Androgen Receptor

   The Androgen Receptor (AR) is a protein inside of certain cells that can bind or capture the androgen hormones testosterone and the more active metabolite 5alpha-dihydrotestosterone (DHT). Once the receptor binds one of the hormones, it causes the receptor to become active and stimulate production of certain proteins inside cells such as PSA.

It is known that AR is required for the normal development of the prostate. If a male animal has no AR, then the prostate will not be created of will be very small when he is born.

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