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Too much of a good thing: Important mechanism in hormone-sensitive breast cancer uncovered
By Dross at 2010-11-24 21:44
 

Two thirds of breast cancers are ERalpha-positive, i.e., many estrogen receptors of the ERalpha- type are found in their cells. "These molecules can interact with the estrogen hormone and, thus, even lead to cancer," explains Dr. Joerg Hoheisel; molecular biologist at DKFZ. "The connection between the levels of the estrogen receptor alpha and the occurrence of breast cancer has been known for some time now. Early-stage breast cancer cells already produce too many of these receptors.

read more | 1836 reads

Discovery halts breast cancer stem cells
By Dross at 2010-11-24 21:41
 

BOSTON (Nov. 23, 2010) —Breast cancer stem cells (CSCs), the aggressive cells thought to be resistant to current anti-cancer therapies and which promote metastasistermterm, are stimulated by estrogen via a pathway that mirrors normal stem cell development. Disrupting the pathway, researchers were able to halt the expansion of breast CSCs, a finding that suggests a new drug therapy target.

read more | 12 comments | 2001 reads

Hebrew University research carries cautionary warning for future stem cell applications
By Dross at 2010-11-23 01:39
 

Jerusalem, November 21, 2010 – Research work carried out at the Hebrew University of Jerusalem arouses a cautionary warning in the growing field of the development of stem cells as a means for future treatment of patients through replacement of diseased or damaged tissues by using the patient's own stem cells. The research indicates a possible danger of cancerous tissue development in the use of such cells.

read more | 1 comment | 1010 reads

Trigger mechanism provides 'quality control' in cell division
By Dross at 2010-11-23 01:27
 

SALT LAKE CITY, November 22, 2010 —Researchers from Huntsman Cancer Institute (HCI) at the University of Utah report that they have identified a previously undiscovered trigger mechanism for a quality control checkpoint at the very end of the cell division process in a paper to be published in the November 29 issue of The Journal of Cell Biology and online today. This trigger mechanism monitors whether the cell's nucleus, where the DNA resides, has the proper structure and delays cell division if the structure is not correct.

read more | 981 reads

Eating a variety of fruit cuts lung cancer risk
By Dross at 2010-11-19 22:07
 

Eating five portions of fruit and vegetables per day is one of the means that experts most frequently recommend for preventing cancer. Now, the European EPIC study carried out by researchers from 10 countries has shown that, in the case of lung cancer, the important thing is not just the quantity but also the variety of fruit consumed, which can reduce the risk by up to 23%.

read more | 1 comment | 1798 reads

Regular exercise reduces large number of health risks including dementia and some cancers
By Dross at 2010-11-16 04:05
 

People who take regular exercise could reduce their risk of developing around two dozen physical and mental health conditions - including some cancers and dementia - and slow down how quickly their body deteriorates as they age.

An extensive research review, published in the December issue of IJCP, the International Journal of Clinical Practice, says that apart from not smoking, being physically active is the most powerful lifestyle choice any individual can make to improve their health.

read more | 1450 reads

Study: Prostate cancer treatment linked to higher rate of colon cancer | University of Michigan Health System
By Dross at 2010-11-16 03:48
 

NN ARBOR, Mich. — Men treated with hormone-based therapy for prostate cancer faced a 30 percent to 40 percent higher risk of colorectal cancer, compared to patients who did not receive this treatment, according to a new study.

read more | 2213 reads

Lasofoxifene reduces breast cancer risk in postmenopausal osteoporotic women
By Dross at 2010-11-05 23:45
 

Lasofoxifene statistically reduced the overall risk of breast cancer, as well as ER positive invasive breast cancer in postmenopausal women with low bone density, according to a study published online in The Journal of the National Cancer Institute.

read more | 1515 reads

Germany - Treatment Protocol for Relapsed Acute Promyelocytic Leukemia (APL) With Arsenic
By Dross at 2010-11-05 04:30
 

Acute promyelocytic leukemiaterm is defined by a characteristic morphology (AML FAB M3/M3v), by the specific translocation t(15;17) and its molecular correlates (PML/RARa and RARa/PML). Thereby it can be separated from all other forms of acute leukemia.

read more | 1758 reads

Discovery shows promise against severe side effects
By Dross at 2010-11-05 03:42
 

November 4, 2010 – (BRONX, NY) -- A team of scientists has found a way to eliminate a debilitating side effect associated with one of the main chemotherapyterm drugs used for treating colon cancer. The strategy used in their preclinical research—inhibiting an enzyme in bacteria of the digestive tract—could allow patients to receive higher and more effective doses of the drug, known as CPT-11 or Irinotecantermterm.

read more | 1492 reads

Protein Folding Contest
By Dross at 2010-11-05 03:10
 

CALL FOR ENTRIES Online Protein Folding Competition for Cash Prizes

read more | 1508 reads

New lymphoma therapy may be more effective with fewer side effects
By Dross at 2010-11-04 22:51
 

Weill Cornell researchers report on targeted therapy to repress protein mutations in diffuse large B-cell lymphomas

NEW YORK (Nov. 3, 2010) -- Diffuse large B-cell lymphomaterm (DLBCL) is a type of aggressive non-Hodgkin's lymphoma that accounts for approximately 40 percent of lymphomas among adults. If left untreated, it is fatal. The existing treatments have a cure rate that is slightly over 50 percent but destroy healthy cells along with the cancer cells.

read more | 1640 reads

Insufficient vitamin D levels in CLL patients linked to cancer progression and death
By Dross at 2010-11-04 22:50
 

ROCHESTER, Minn. -- Researchers at Mayo Clinic (http://www.mayoclinic.org/) have found a significant difference in cancer progression and death in chronic lymphocytic leukemiaterm (CLL) patients who had sufficient vitamin D (http://www.mayoclinic.com/health/vitamin-d/NS_patient-vitamind) levels in their blood compared to those who didn't.

read more | 1532 reads

Rictor protein offers scientists a new molecular target for cancer therapies
By Dross at 2010-10-29 21:53
 

BOSTON – The discovery that a protein called Rictor plays a key role in destroying a close cousin of the AKT oncogene could provide scientists with a new molecular target for treating certain cancers, including breast cancer. Described in the September 2010 issue of the journal Molecular Cell, the study was led by scientists at Beth Israel Deaconess Medical Center (BIDMC).

read more | 1566 reads

People with specific kind of lung cancer respond to new targeted treatment
By Dross at 2010-10-29 21:45
 

AURORA, Colo. (Oct. 28, 2010) - A study in the New England Journal of Medicine shows more than half of patients with a specific kind of lung cancer are responding positively to a treatment that targets the gene that drives their cancer.

read more | 4 comments | 1893 reads

 
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