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New research: 'Un-growth hormone' increases longevity
By Dross at 2011-01-04 03:47

ST. LOUIS – A compound which acts in the opposite way as growth hormone can reverse some of the signs of aging, a research team that includes a Saint Louis University physician has shown. The finding may be counter-intuitive to some older adults who take growth hormone, thinking it will help revitalize them.

Their research was published in the Dec. 6 online edition of the Proceedings of the National Academy of Sciences.

read more | 11388 reads

Some cancer drugs may block cellular cross talk but not kill cancer cells
By Dross at 2010-12-23 03:57

New data from the University of Colorado Cancer Center could alter how drugs are evaluated 


AURORA, Colo. (Dec. 22, 2010)—A class of drugs thought to kill cancer cells may in fact block “cross talk” between the cancer cell and normal immune cells, resulting in reduced cancer growth and spread—a discovery that could significantly alter the way cancer drugs are evaluated in the future.

read more | 3 comments | 8363 reads

Blocking the critical structure that lets cancer cells move -- their feet
By Dross at 2010-12-17 03:19

Scientists now know that some cancer cells spread, or metastasize, throughout the body the old-fashioned way -- by using their feet. But researchers at Duke Cancer Institute have discovered a way to short-circuit their travels by preventing the development of these feet, called invadopodia. This discovery is even more important because preventing the development of these "feet" also eliminates the action of proteins present in the feet that burn through intact tissue and let cancer cells enter new cells.

read more | 2377 reads

Researchers make critical leukemia stem cell discovery
By Dross at 2010-12-15 05:33

Researchers at King's College London have discovered that leukaemic stem cells can be reversed to a pre-leukaemic stage by suppressing a protein called beta-catenin found in the blood.

They also found that advanced leukaemic stem cells that had become resistant to treatment could be 're-sensitised' to treatment by suppressing the same protein.

read more | 3024 reads

A protein called cFLIP makes tumor cells in breast cancer resistant to treatments
By Dross at 2010-12-15 04:26

Researchers at the Andalusian Institute for Molecular Biology and Regenerative Medicine (CABIMER) and the University of Granada found that cFLIP –an inhibitor of death ligand-induced apoptosis– is not only essential in breast tumor cells resistance to TRAIL treatments (a death ligand with a potent therapeutic potential against cancer), but this protein is also key to the survival of such cancer cells.

read more | 2124 reads

Avastin Regrowth (Rebound)
By gdpawel at 2010-12-10 04:32

A study published in the Journal of Clinical Investigation (Volume 116, Number 10) tested human serum, derived from colon cancer patients who had either been treated with chemotherapyterm alone or with chemotherapy + Avastinterm. Serum from Avastin treated patients actually support endothelial cell growth in cell culture better than serum from control patients, without Avastin treatment.

read more | 5 comments | 3535 reads

Use of low-dose aspirin associated with improved performance of test for detecting colorectal cancer
By Dross at 2010-12-09 04:15

Use of low-dose aspirin prior to a newer type of fecal occult blood test is associated with a higher sensitivity for detecting advanced colorectal tumors, compared to no aspirin use, according to a study in the December 8 issue of JAMA.

read more | 1783 reads

Accurate diagnosis of prostate cancer with ultrasound
By Dross at 2010-12-09 02:24

Prostate cancer is the most common type of cancer among men, but its diagnosis has up to now been inaccurate and unpleasant. Researchers at Eindhoven University of Technology (TU/e), in cooperation with AMC Amsterdam, have developed an imaging technology that can accurately identify tumors. The technology is based on ultrasound, and also has the potential to assess how aggressive tumors are. This can lead to better and more appropriate treatment, and to cost savings in health care.

read more | 2 comments | 1850 reads

New microscopy tracks molecules in live tissue at video rate
By Dross at 2010-12-04 02:05


A novel type of biomedical imaging, made possible by new advances in microscopy from scientists at Harvard University, is so fast and sensitive it can capture "video" of blood cells squeezing through capillaries.

Researchers led by Harvard's Brian G. Saar, Christian W. Freudiger, and X. Sunney Xie describe the work this week in the journal Science.

read more | 1344 reads

Genetic mutations associated with increased PSA and prostate cancer
By Dross at 2010-12-04 01:49


Austrian researchers have uncovered mutations throughout the mitochondrial genome that are associated with prostate cancer. An exciting aspect of the study, published by Cell Press on December 2 in the American Journal of Human Genetics, is the association of tRNA mutations with elevated levels of prostate-specific antigen (PSA) in Austrian men diagnosed with various stages of prostate cancer.

read more | 1759 reads

New clue in leukemia mystery: Researchers identify 'poison' employed by deadly enzyme mutations
By Dross at 2010-12-04 00:16

NEW YORK (Dec. 2, 2010) -- There is new hope for people with acute myelogenous leukemiaterm (AML), a fast-growing cancer of the blood and bone marrow. Research led by Weill Cornell Medical College and published today in the online edition of the journal Cancer Cell reveals a surprising and unexpected cancer-causing mechanism. The investigators discovered that newly identified mutant enzymes in AML create a chemical poison to cause leukemia.

read more | 2738 reads

Arthritis medication has anti skin cancer effects
By Dross at 2010-12-02 23:53

Arthritis sufferers rejoice, your use of the prescription medication celebrex (celexocib), a cox-2 inhibitor, could spare you from some of the sun effects that lead to basal and squamous cell carcinomaterm. According to a study published in the Journal of the National Cancer Institute Use of the drug led to a 68 percent reduction in basal cell carcinomas and a 58 percent reduction in squamous cell carcinomas in patients at high risk for skin cancer.

read more | 2124 reads

Mad cow disease - alzheimers and transmission
By Dross at 2010-12-02 05:47

Aside from prions -- which can trigger a cascade of protein misfolding associated with "mad cow disease" and Creutzfeldt-Jakob disease -- there has been no evidence that other neurodegenerative diseases associated with protein misfolding are transmissible between humans by an infectious agent.  But in a Report in the 12 Nov 2010 Science read more | 1282 reads

Tumors bring their own support cells when forming metastases
By Dross at 2010-12-02 00:14


The process of metastasistermterm requires that cancer cells traveling from a primary tumor find a hospitable environment in which to implant themselves and grow. A new study from Massachusetts General Hospital (MGH) Cancer Center researchers finds that circulating tumor cells prepare this environment by bringing along from their original site noncancerous cells that support tumor growth. The report has been published online in PNAS Early Edition.

read more | 1 comment | 1467 reads

Finger length points to prostate cancer risk
By Dross at 2010-12-01 23:39


Men who have long index fingers are at lower risk of prostate cancer, a new study published today in the British Journal of Cancer has found.

read more | 1 comment | 2129 reads


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