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New drug overcomes resistance in patients with rare sarcoma
By admin at 2012-11-25 19:49

A new targeted drug demonstrated its ability to control metastatic gastrointestinal stromal tumor, an uncommon and life-threatening form of sarcoma, after the disease had become resistant to all existing therapies, report investigators at Dana-Farber Cancer Institute who led the worldwide clinical trial.

read more | 1484 reads

Stem cells develop best in 3D
By admin at 2012-11-25 18:45

Stem cells are responsible for tissue growth and tissue repair after injury. Therefore, the discovery that these vital cells grow better in a three-dimensional environment is important for the future treatment of disease with stem cell therapy.

read more | 1 comment | 1727 reads

Diagnostic accuracy may be improved via 3D scanning technique
By admin at 2012-11-21 20:08

According to the results of a new multi-center study published in the journal Radiology, the use of three-dimensional breast imaging, known as tomosynthesis, could improve diagnostic accuracy.

read more | 12 comments | 2719 reads

New Clinical Study Shows Test That Doubles Chemotherapy Response Rate
By gdpawel at 2012-11-05 02:53

Using only FDA-approved, standard lung cancer drugs available to all oncologists, a process of laboratory selection provided a 64.5 percent response rate - more than double the national average of 30 percent (p = 0.00015), well established in medical literature. More importantly, the median overall survival of 21.3 months was nearly two-fold longer than the best results of 13.5 months reported for non-assay based standard treatments. Strikingly, among the stage IV (metastatic) patients, there are several who remain alive approaching eight years since diagnosis.

read more | 2 comments | 1946 reads

Molecular Biology vs Cellular Biology
By gdpawel at 2012-09-27 09:45

There is a growing litany of observations that call into question molecular biologist's preternatural fixation on genomic analyses. Human biology is not simple and malignantly transformed cells more complex still. Investigators who insist upon using genomic platforms to force disorderly cells into artificially ordered sub-categories, have once again been forced to admit that these oversimplifications fail to provide the needed insights for the advancement of cancer therapeutics.

read more | gdpawel's blog | 2762 reads

Susan G Komen
By admin at 2012-08-15 03:53

Susan G Komen Race for the Cure

admin's blog | 2 comments | 2729 reads

Susan G Komen
By Dross at 2012-08-15 03:51
Dross's blog | 2302 reads

Miami Project Gets Green Light to Begin Schwann Cell Human Trial | Miller School of Medicine | University of Miami
By Dross at 2012-08-05 03:46

 The Miami Project to Cure Paralysis, a Center of Excellence at the University of Miami Miller School of Medicine, has received permission from the Food and Drug Administration to begin a revolutionary Phase 1 clinical trial to evaluate the safety of transplanting human Schwann cells to treat patients with recent spinal cord injuries.

read more | 1 comment | 2134 reads

Laboratory Oncology
By gdpawel at 2012-07-27 14:51

Larry Weisenthal, M.D., PhD.

The tumor holds the key to a patient's clinical outcome and survival. Each specimen must be individualized. Performing cell function analysis deserves the same degree of professional time and attention as major extirpative or debulking surgery or radiotherapy.

read more | 3 comments | 2412 reads

Stem cell research aids understanding of cancer
By Dross at 2012-07-20 20:25

The study, published in the journal Stem Cell, adds to our understanding of the role of stem and next stage progenitor cells in tissue regeneration and in the diagnosis and treatment of cancer. While stem cells are known to reside in organs such as the liver and pancreas, they are difficult to isolate. The new findings show that an antibody developed by the team can be used to capture the stem cells.

read more | 5 comments | 3717 reads

Scientists discover melanoma-driving genetic changes caused by sun damage
By Dross at 2012-07-20 00:03

HOUSTON — It's been a burning question in melanoma research: Tumor cells are full of ultraviolet (UV)-induced genetic damage caused by sunlight exposure, but which mutations drive this cancer?

None have been conclusively tied to melanoma. The sheer abundance of these passenger mutations has obscured the search for genetic driver mutations that actually matter in melanoma development and progression.

read more | 5 comments | 3543 reads

Preclinical data support ongoing clinical trials testing IDO inhibitors as a treatment for cancer
By Dross at 2012-07-19 22:36

PHILADELPHIA — Inhibitors of indoleamine 2,3-dioxygenase (IDO) are being assessed in clinical trials as a potential treatment for recurrent or refractory solid tumors.

read more | 1 comment | 2953 reads

Help us purchase lab equipment
By admin at 2012-07-19 07:49

Please consider helping us achieve our goals. The funds will be put towards a bioreactor and flow cytometerterm to further our research. Government spending is sparse these days.

admin's blog | 2757 reads

Personalized Medicine And Cancer Care
By gdpawel at 2012-06-24 00:42

As we enter the era of "personalized" medicine, it is time to take a fresh look at how we evaluate treatments for cancer patients. More emphasis is needed matching treatment to the patient. Patients would certainly have a better chance of success had their cancer been chemo-sensitive rather than chemo-resistant, where it is more apparent that chemotherapy improves the survival of patients, and where identifying the most effective chemotherapy would be more likely to improve survival.

read more | 8 comments | 4945 reads

Randomized Clinical Trial Paradigm
By gdpawel at 2012-05-13 00:19

The mindset of cancer medicine is to think it's great science to identify the best treatment to give to the average patient is through prospective, randomized trials. We have produced an entire generation of investigators in clinical oncology who believe that the only valid form of clinical research is to perfrom well-designed, prospective randomized trials in which patients are randomized to receive one empiric drug combination versus another empiric drug combination. Do cancer cells like Coke or Pepsi?

read more | 27 comments | 7428 reads


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