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Old 01-16-2008, 03:06 PM
Dross Dross is offline
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Default Pancytopenia MDS may reflect stromal changes and longer time to engraftment post tran

A new story entry has been added:

Pancytopenia MDS may reflect stromal changes and longer time to engraftment post transplant

Quote:
It has recently been shown that patients with myelodysplastic syndrome (MDS) may find that their time to stem cell engraftment post transplant is delayed beyond that seen by Acute Myeloid Leukemia transplant patients (a more serious disease.) The thought behind these results is that the bone marrow's stroma (matrix cells) was not providing sufficient signal to the blood progenitor cells before the transplant took place, whereas the AML patients may have had progenitor cells with more serious mutations in their dna which would not have responded properly even if the stroma's signals were being provided. Therefore in many AML patients, transplanted stem cells are able to engraft quickly because the matrix environment is healthy and able to support the division and growth of new progenitors.
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Old 11-20-2009, 05:29 PM
Ship Ship is offline
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Default pancytopenia

Is there anyone around the forum who has pancytopenia? What kind of treatment are you taking (I realize that it can vary due to the cause of the pancytopenia and other issues)?

Last edited by Dross : 01-06-2010 at 01:45 PM.
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Old 01-06-2010, 01:45 PM
Dross Dross is offline
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Default Csf

Did your physician suggest G-CSF or GM-CSF?
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